Research Areas

Climate Change and Human Health
Climate change is expected to bring major shifts in weather patterns and can lead to more extreme events like heat waves, drought, and flooding. These climate-related changes affect various health outcomes that can lead to poorer quality of life and push national health systems beyond their limits. To quantify health impacts of climate change, we perform analysis of global level datasets using advanced statistical modeling tools in collaboration with various universities and research institutions internationally. These outputs are useful for the planning of adaptation and mitigation efforts by international institutions and national governments.
  • Hayon Michelle Choi, Whanhee Lee, Dominic Roye, Seulkee Heo, Aleš Urban, Alireza Entezari, Ana Maria Vicedo-Cabrera, Antonella Zanobetti, Antonio Gasparrini, Antonis Analitis, Aurelio Tobias, Ben Armstrong, Bertil Forsberg, Carmen Íñiguez, Christofer Åström, Chris Fook Sheng Ng, Ene Indermitte, Eric Lavigne, Fatemeh Mayvaneh, Fiorella Acquaotta, Francesco Sera, Hans Orru, Ho Kim, Jan Kyselý, Joana Madueira, Joel Schwartz, Jouni J.K. Jaakkola, Klea Katsouyanni, Magali Hurtado Diaz, Martina S. Ragettli, Masahiro Hashizume, Mathilde Pascal, Niilo Ryti, Noah Scovronick, Samuel Osorio, Shilu Tong, Xerxes Seposo, Yasushi Honda, Yoonhee Kim, Yue-Liang Guo, Yuming Guo, Michelle L. Bell. Corrigendum to “Effect modification of greenness on the association between heat and mortality: A multi-city multi-country study”. eBioMedicine. 2023, 87: 104396.

    Read the Article

  • Chua PLC, Seposo XT, Hashizume M. Heat exposure and the transmission of infectious diseases. In: Guo Y, Li S, eds. Heat exposure and human health in the context of climate change. Amsterdam, the Netherlands, Oxford, United Kingdom, and Cambridge, USA. Elsevier. 2023: 189-221.

    Read the Article

  • Ortiz AMD, Chua PLC, Salvador D, Dyngeland C, Albao JDG, Abesamis RA. The impacts of tropical storms on the nexus of food, health, and biodiversity. The World Health Organization Bulletin.
  • Szu Yu Lin; Chris Fook Sheng Ng; Yoonhee Kim; Zin Wai Htay; Alton Quan Cao; Rui Pan; Masahiro Hashizume. Ambient temperature and nervous system diseases-related mortality in Japan from 2010 to 2019: A time-stratified case-crossover analysis. Science of The Total Environment. 2023-01. 10.1016/j.scitotenv.2023.161464.

    Read the Article

  • Ortiz AM, Chua PL, Salvador D, Dyngeland C, Albao JD, Abesamis RA. Impacts of tropical cyclones on food security, health and biodiversity. Bulletin of the World Health Organization. 2023;101(2):152-4.

    Read the Article

  • Paul LC Chua, Chris Fook Sheng Ng, Lina Madaniyazi, Xerxes Seposo, Miguel Antonio Salazar, Veronika Huber, Masahiro Hashizume. Projecting temperature-attributable mortality and hospital admissions due to enteric infections in the Philippines. Environmental Health Perspectives. 2022; 130(2): 027011.

    Read the Article

  • Paul LC Chua, Chris Fook Sheng Ng, Aurelio Tobias, Xerxes Seposo, Masahiro Hashizume. Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis. Lancet Planetary Health. 2022; 6(3): e202-e218.

    Read the Article

  • Chua PLC, Ng CFS, Tobias A, Seposo XT, Hashizume M. Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis. The Lancet Planetary Health. 2022; 6(3): e202-e218. doi:10.1016/S2542-5196(22)00003-1
  • Chua PLC, Ng CFS, Madaniyazi L, Seposo X, Salazar MA, Huber V, Hashizume M. Projecting temperature-attributable mortality and hospital admissions due to enteric infections in the Philippines. Environmental Health Perspectives. 2022; 130(2): 027011. doi:10.1289/EHP9324
  • Estanislao RD, Salazar MA, Sigua JA, Chua PLC, Dorotan MM. Collaboration and capacity for climate change and health research: an analysis of stakeholders in the Philippines. The Journal of Climate Change and Health. 2022; 6:100107. doi:10.1016/j.joclim.2021.100107
  • Chua PLC, Ng CFS, Tobias A, Seposo XT, Hashizume M.. Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis. Lancet Planet Health. 2022;6(3):e202-e218. doi: 10.1016/S2542-5196(22)00003-1.

    Read the Article

  • Xerxes Tesoro Seposo, Lina Madaniyazi, Chris Fook Sheng Ng, Masahiro Hashizume, Yasushi Honda. COVID-19 pandemic modifies temperature and heat-related illness ambulance transport association in Japan: A nationwide observational study. Environmental Health. 2021; 20: 122.

    Read the Article

  • Aurelio Tobías, Masahiro Hashizume, Yasushi Honda, Francesco Sera, Chris Fook Sheng Ng, Yoonhee Kim, Dominic Roye, Yeonseung Chung, Tran Ngoc Dang, Ho Kim, Whanhee Lee, Carmen Íñiguez, Ana Vicedo-Cabrera, Rosana Abrutzky, Yuming Guo, Shilu Tong, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Eric Lavigne, Patricia Matus Correa, Nicolás Valdés Ortega, Haidong Kan, Samuel Osorio, Jan Kyselý, Aleš Urban, Hans Orru, Ene Indermitte, Jouni J. K. Jaakkola, Niilo R.I. Ryti, Mathilde Pascal, Veronika Huber, Alexandra Schneider, Klea Katsouyanni, Antonis Analitis, Alireza Entezari, Fatemeh Mayvaneh, Patrick Goodman, Ariana Zeka, Paola Michelozzi, Francesca de'Donato, Barrak Alahmad, Magali Hurtado Diaz, César De la Cruz Valencia, Ala Overcenco, Danny Houthuijs,Caroline Ameling, Shilpa Rao, Francesco Di Ruscio, Xerxes Seposo, Baltazar Nunes, João Paulo Teixeira, Iulian Horia Holobâc, Noah Scovronick, Fiorella Acquaotta, Bertil Forsberg, Christofer Åström, Martina S. Ragettli, Yue-Liang Leon Guo, Bing-Yu Chen, Shanshan Li, Valentina Colistro, Antonella Zanobetti, Joel Schwartz, Do Van Dung, Ben Armstrong, Antonio Gasparrini. Geographical variations of the minimum mortality temperature at a global scale: a multi-country study. Environmental Epidemiology. 2021; 5: e169.

    Read the Article

  • Paul LC Chua, Chris Fook Sheng Ng, Adovich Rivera, Eumelia Salva, Miguel Antonio Salazar, Veronika Huber, Masahiro Hashizume. Association between ambient temperature and severe diarrhoea in the National Capital Region, Philippines. International Journal of Environmental Research and Public Health. 2021; 18: 8191.

    Read the Article

  • Lina Madaniyazi, Yeonseung Chung, Yoonhee Kim, Aurelio Tobias, Chris Fook Sheng Ng, Xerxes Seposo, Yuming Guo, Yasushi Honda, Antonio Gasparrini, Ben Armstrong, Masahiro Hashizume. Seasonality of mortality under a changing climate: a time-series analysis of mortality in Japan between 1972 and 2015. Environmental Health and Preventive Medicine. 2021

    Read the Article

  • Lina Madaniyazi, Chris Fook Sheng Ng, Xerxes Seposo, Michiko Toizumi, Lay Myint Yoshida, Yasuda Honda, Masahiro Hashizume. Role of temperature, influenza and other local characteristics in seasonality of mortality: a population-based time-series study in Japan. BMJ Open. 2021; 11: e044876.

    Read the Article

  • Lina Madaniyazi, Ben Armstrong, Yeonseung Chung, Chris Fook Sheng Ng, Xerxes Seposo, Yoonhee Kim, Aurelio Tobias, Yuming Guo, Francesco Sera, Yasushi Honda, Antonio Gasparrini, Masahiro Hashizume. Multi-country Multi-city (MCC) Collaborative Research Network. Seasonal variation in mortality and the role of temperature: a multi-country multi-city study. International Journal of Epidemiology. 2021; online ahead of print.

    Read the Article

  • Paul LC Chua, Veronika Huber, Chris Fook Sheng Ng, Xerxes T Seposo, Lina Madaniyazi, Simon Hales, Alistair Woodward, Masahiro Hashizume. Global Projections of temperature-attributable mortality due to enteric infections: an aetiology-specific modelling study. Lancet Planetary Health. 2021; 5: e436:e445.

    Read the Article

  • Chua PLC, Ng CFS, Rivera A, Salva E, Salazar MA, Huber V, Hashizume M. Association between ambient temperature and severe diarrhoea in the National Capital Region, Philippines. International Journal of Environmental Research and Public Health. 2021; 18(15): 8191. doi: 10.3390/ijerph18158191.
  • Chua PLC, Huber V, Ng CFS, Seposo X, Madaniyazi L, Hales S, Woodward A, Hashizume M. Global projections of temperature-attributable mortality due to enteric infections. The Lancet Planetary Health. 2021; 5(7): e436-e445. doi: 10.1016/S2542-5196(21)00152-2.
  • Madaniyazi L, Armstrong B, Chung Y, Ng CFS, Seposo X, Kim Y, Tobias A, Guo Y, Sera F, Honda Y, Gasparrini A, Hashizume M: Multi-country Multi-city (MCC) Collaborative Research Network. Seasonal variation in mortality and the role of temperature: a multi-country multi-city study. Int J Epidemiol. 2021 doi: 10.1093/ije/dyab143.

    Read the Article

  • Chua PLC, Huber V, Ng CFS, Seposo XT, Madaniyazi L, Hales S, Woodward A, Hashizume M. Global projections of temperature-attributable mortality due to enteric infections: a modelling study. Lancet Planet Health. 2021;5(7):e436-e445. doi: 10.1016/S2542-5196(21)00152-2.

    Read the Article

  • Kisung Sim, Yoonhee Kim, Masahiro Hashizume, Antonio Gasparrini, Ben Armstrong, Francesco Sera, Chris Fook Sheng Ng, Yasushi Honda, Yeonseung Chung. Spatio-temporal heterogeneity in the temperature-suicide association: a nationwide study in Japan from 1972-2015. Environmental International. 2020; 142: 105829.

    Read the Article

  • Hashizume M, Kim Y, Ng CFS, Chung Y, Madaniyazi L, Bell ML, Guo YL, Kan H, Honda Y, Yi SM, Kim H, Nishiwaki Y. Health effects of Asian dust: a systematic review and meta-analysis. Environ Health Perspect. 2020 Jun;128(6):66001. doi: 10.1289/EHP5312.

    Read the Article

  • Yoonhee Kim, J. Venkata Ratnam, Takeshi Doi, Yushi Morioka, Swadhin Behera, Ataru Tsuzuki, Noboru Minakawa, Neville Sweijd, Philip Kruger, Rajendra Maharaj, Chisato Imai, Chris Fook Sheng Ng, Yeonseung Chung. Malaria predictions based on seasonal climate forecasts in South Africa: A time series distributed lag nonlinear model. Scientific Reports. 2019; 9(1):17882.

    Read the Article

  • Yoonhee Kim, Ho Kim, Antonio Gasparrini, Ben Armstrong, Yasushi Honda, Yeonseung Chung, Chris Fook Sheng Ng, Aurelio Tobias, Carmen Íñiguez, Eric Lavigne, Francesco Sera, Ana M. Vicedo-Cabrera, Martina S. Ragettli, Noah Scovronick, Fiorella Acquaotta, Bing-Yu Chen, Yue-Liang Leon Guo, Xerxes Seposo, Tran Ngoc Dang, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Anna Kosheleva, Antonella Zanobetti, Joel Schwartz, Michelle L. Bell, Masahiro Hashizume. Suicide and Ambient Temperature: A Multi-City Multi-Country Study. Environmental Health Perspectives. 2019; 127(11): 117007.

    Read the Article

  • Yeonseung Chung, Daewon Yang, Antonio Gasparrini, Ana M. Vicedo-Cabrera, Chris Fook Sheng Ng, Yoonhee Kim, Yasushi Honda, Masahiro Hashizume. Changing susceptibility to non-optimum temperatures in Japan, 1972-2012: the role of climate, demographic and socio-economic factors. Environmental Health Perspectives. 2018; 126(5): 057002.

    Read the Article

  • Chua PLC, Dorotan MC, Sigua JA, Estanislao RD, Hashizume M, Salazar MA. Scoping review of climate change and health research in the Philippines: A complementary tool in research agenda-setting. International Journal of Environmental Research and Public Health. 2019; 16(14): 2624. doi:10.3390/ijerph16142624.
  • Chris Fook Sheng Ng, Melanie Boeckmann, Kayo Ueda, Hajo Zeeb, Hiroshi Nitta, Chiho Watanabe, Yasushi Honda. Heat-related mortality: effect modification and adaptation in Japan from 1972 to 2010. Global Environmental Change. 2016; 39: 234–243. https://doi.org/10.1016/j.gloenvcha.2016.05.006.

    Read the Article

  • Teruyuki Nakajima, Ryoichi Imasu, Akinori Takami, Daisuke Goto, Haruo Tsuruta, Junya Uchida, Tie Dai, Shota Misawa, Kayo Ueda, Chris Fook Sheng Ng, Chiho Watanabe, Shoko Konishi, Yousuke Sato, Atsushi Higuchi, Yuji Masutomi, Akinobu Murakami, Kazuaki Tsuchiya, Hiroaki Kondo, Yousuke Niwa, Kei Yoshimura, Toshimasa Ohara, Yu Morino, Nick Schutgens, Kengo Sudo, Toshihiko Takemura, Toshiro Inoue, Yutaka Arai, Ryo Murata, Ryoma Yonemoto, Trieu Tran Thi Ngoc, Mitsuo Uematsu, Masaki Satoh, Hirofumi Tomita, Hisashi Yashiro, Hara Masayuki. Development of Seamless Chemical Assimilation System and Its Application for Atmospheric Environmental Materials. Journal of the Japan Society for Simulation Technology. 2015; 34(2): 104-114.

    Read the Article

  • Daisuke Goto, Tie Dai, Masaki Satoh, Hirofumi Tomita, Junya Uchida, Shoto Misawa, Toshiro Inoue, Haruo Tsuruta, Kayo Ueda, Chris Fook Sheng Ng, Akinori Takami, Nobuo Sugimoto, Atsushi Shimizu, Toshimasa Ohara, Teruyuki Nakajima. Application of a global nonhydrostatic model with a stretched-grid system to regional aerosol simulations around Japan. Geoscientific Model Development 2015. 2015; 8: 235–259. https://doi.org/10.5194/gmd-8-235-2015.

    Read the Article

  • Chisa Shinsugi, Andrew Stickley, Shoko Konishi, Chris Fook Sheng Ng, Chiho Watanabe. Seasonality of child and adolescent injury mortality in Japan, 2000-2010. Environmental Health and Preventive Medicine 2014. 2014; 20(1): 36–43. https://doi.org/10.1007/s12199-014-0421-7.

    Read the Article

  • Hashizume M. IPCC, 2014: Climate Change 2014:Impacts, Adaptation, and Vulnerability. Part B: Regional Aspects. Contribution of Working Group II to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change [Barros, V.R., C.B. Field, D.J. Dokken, M.D. Mastrandrea, K.J. Mach, T.E. Bilir, M. Chatterjee, K.L. Ebi, Y.O. Estrada, R.C. Genova, B. Girma, E.S. Kissel, A.N. Levy, S. MacCracken, P.R. Mastrandrea, and L.L. White (eds.)]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA, 688 2014

    Read the Article

  • Hashizume M, Faruque ASG, Dewan AM. Rainfall dependence of hospital visits of Aeromonas-positive diarrhoea in Dhaka. In AM Dewan and RJ Corner (Eds) Dhaka Megacity: Geospatial Perspecitives on Urbanization, Environment and Health, Springer Geography. 2013:333-344.

    Read the Article

  • Hashizume M. Precipitation and Flood Hazards: Health Effects, Risks, and Impacts. In R Pielke, Sr. (Eds) Climate Vulnerability: Understanding and Addressing Threats to Essential Resources. Elsevier Inc. Academic Press. 2013:115-124.

    Read the Article

  • Hashizume M (Contributing author) for Handmer, J., Y. Honda, Z.W. Kundzewicz, N. Arnell, G. Benito, J. Hatfield, I.F. Mohamed, P. Peduzzi, S. Wu, B. Sherstyukov, K. Takahashi, and Z. Yan, 2012: Changes in impacts of climate extremes: human systems and ecosystems. In: Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation [Field, C.B., V. Barros, T.F. Stocker, D. Qin, D.J. Dokken, K.L. Ebi, M.D. Mastrandrea, K.J. Mach, G.-K. Plattner, S.K. Allen, M. Tignor, and P.M. Midgley (eds.)]. A Special Report of Working Groups I and II of the Intergovernmental Panel on Climate Change (IPCC). Cambridge University Press, Cambridge, UK, and New York, NY, USA, pp. 231-290. 2012

    Read the Article

  • Kim Y, Kim H, Gasparrini A, Armstrong B, Honda Y, Chung Y, Ng CFS, Tobias A, Iniguez C, Lavigne E, Sera F, Vicedo-Cabrera AM, Ragettli MS, Scovronick N, Acquaotta F, Chen BY, Guo YLL, Seposo X, Dang TN, Coelho MSZS, Saldiva PHN, Kosheleva A, Zanobetti A, Schwartz J, Bell ML, Hashizume M. Suicide and ambient temperature: a multi-country multi-city study. Environ Health Perspect. 2019;127(11):117007. doi:10.1289/EHP4898

    Read the Article

  • Onozuka D, Gasparrini A, Sera F, Hashizume M, Honda Y. Modeling future projections of temperature-related excess morbidity due to infectious gastroenteritis under climate change conditions in Japan. Environ Health Perspect. 2019;127(7):77006. doi: 10.1289/EHP4731.

    Read the Article

  • Chung Y, Yang DW, Gasparrini A, Vicedo-Cabrera AM, Ng CFS, Kim Y, Honda Y, Hashizume M. Changing susceptibility to non-optimum temperatures in Japan, 1972-2012: the role of climate, demographic and socio-economic factors. Environ Health Perspect. 2018 DOI:10.1289/EHP2546.

    Read the Article

  • Nakamura T, Hashizume M, Ueda K, Shimizu A, Takeuchi A, Kubo T, Hashimoto K, Moriuchi H, Odajima H, Kitajima T, Tashiro K, Tomimasu K, Nishiwaki Y. Asian dust and pediatric emergency visits due to bronchial asthma and respiratory diseases in Nagasaki, Japan. J Epidemiol. 2016;26(11):593-601.

    Read the Article

  • Gasparrini A, Guo Y, Hashizume M, Lavigne E, Zanobetti A, Schwartz J, Tobias A, Tong S, Rocklov J, Forsberg B, Leone M, De Sario M, Bell ML, Guo YLL, Wu CF, Kan H, Yi SM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PH, Honda Y, Kim H, Armstrong B. Mortality risk attributable to high and low ambient temperature: a multi-country study. The Lancet. 2015;386(9991):369-375

    Read the Article

  • Gasparrini A, Guo Y, Hashizume M, Kinney PL, Petkova EP, Lavigne E, Zanobetti A, Schwartz JD, Tobias A, Leone M, Tong S, Honda Y, Kim H, Armstrong BG. Temporal variation in heat-mortality associations: a multicountry study. Environ Health Perspect. 2015;123:1200-1207.

    Read the Article

  • Takahashi N, Nakao R, Ueda K, Ono M, Kondo M, Honda Y, Hashizume M. Community trial on heat related-illness prevention behaviors and knowledge for the elderly. Int. J. Environ. Res. Public Health. 2015;12(3):3188-3214.

    Read the Article

  • Hashizume M, Chaves LF, Minakawa N. Indian Ocean Dipole drives malaria resurgence in East African highlands. Scientific Reports. 2012:2;269 doi:10.1038/srep00269.

    Read the Article

  • Milojevic A, Armstrong B, Hashizume M*, McAllister K, Faruque ASG, Yunus M, Streatfield PK, Moji K, Wilkinson P. Health effects of flooding in rural Bangladesh. Epidemiology. Kenneth Rothman Epidemiology Prize 2013. 2012;23:107-115.

    Read the Article

  • Hashizume M, Faruque ASG, Terao T, Yunus M, Streatfield K, Yamamoto T, Moji K. The Indian Ocean Dipole and cholera incidence in Bangladesh: A time series analysis. Environmental Health Perspectives. 2011;119:239-244.

    Read the Article

  • Hashizume M, Faruque ASG, Wagatsuma Y, Hayashi T, Armstrong B. Cholera in Bangladesh: Climatic components of seasonal variation. Epidemiology. 21:706-710, 2010.

    Read the Article

  • Hashizume M, Terao T, Minakawa N. The Indian Ocean Dipole and malaria risk in the highlands of western Kenya. Proc Natl Acad Sci U S A. 2009;106:1857-62.

    Read the Article

  • Hashizume M, Wagatsuma Y, Hayashi T, Saha SK, Streatfield K, Yunus M. The effect of temperature on mortality in rural Bangladesh: a population based time-series study. International Journal of Epidemiology. 2009;38(6):1689-1697.

    Read the Article

  • Hashizume M, Armstrong B, Wagatsuma Y, Faruque ASG, Hayashi T, Sack DA. Rotavirus infections and climate variability in Dhaka, Bangladesh: a time-series analysis. Epidemiology and Infection. 2008;136:1281-9.

    Read the Article

  • Hashizume M, Wagatsuma Y, Faruque ASG, Hayashi T, Paul R. Hunter, Armstrong B, Sack DA. Factors determining vulnerability to diarrhoea during and after severe floods in Bangladesh. Journal of Water and Health. 2008;6:323-32.

    Read the Article

  • Hashizume M, Armstrong B, Hajat S, Wagatsuma Y, Faruque ASG, Hayashi T, Sack DA. The effect of rainfall on the incidence of cholera in Bangladesh. Epidemiology. 2008;19:103-10.

    Read the Article

  • Hashizume M, Armstrong B, Hajat S, Wagatsuma Y, Faruque ASG, Hayashi T, Sack DA. Association between climate variability and hospital visits for non-cholera diarrhoea in Bangladesh: effects and vulnerable groups. International Journal of Epidemiology. 2007;36:1030-7.

    Read the Article